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Application and safety evaluation of silicone silicone oil in the pharmaceutical field
Source:iotachem.com
PostTime:2025-04-03 09:46:02



Silicone silicone oil has been widely used in the pharmaceutical field because of its excellent biocompatibility and chemical stability.This article will discuss its specific application and safety evaluation.


Application area
Drug carrier: Silicone silicone oil is commonly used in controlled-release drug systems as a carrier or matrix for drugs.It can delay the release rate of the drug, improve the efficacy of the drug and reduce side effects.For example, in eye drops and skin topical drugs, silicone silicone oil can enhance the adhesion and permeability of drugs.


Medical device lubrication: In syringes, catheters and surgical instruments, silicone silicone oil as a lubricant can reduce friction, improve the efficiency of equipment use and patient comfort.Its chemical inertness ensures that it will not react with drugs or biological tissues.


Preparation additives: In topical preparations such as ointments, creams and gels, silicone silicone oil can improve the texture and ductility of the product, making it easier to apply and absorb.


Security assessment
The safety of silicone silicone oil in pharmaceutical applications has been extensively studied.Its non-toxic, non-irritating and low sensitization make it an ideal pharmaceutical material.However, the following points still need to be noted:


Purity requirements: Pharmaceutical grade silicone silicone oil must be strictly purified to ensure that it does not contain harmful impurities.


Dosage: Excessive use may cause local discomfort or allergic reactions, so the amount used needs to be strictly controlled.


Long-term effects: Although the safety of short-term use is high, the effects of long-term use still need further research.


Future outlook
With the advancement of pharmaceutical technology, the application potential of silicone silicone oil in the field of personalized medicine and bioprinting will be further released.For example, in 3D printing drugs and medical devices, the high precision and biocompatibility of silicone silicone oils will play an important role.
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